Effects of xylazine on acid-base balance and arterial blood-gas tensions in goats under different environmental temperature and humidity conditions.

نویسندگان

  • E G Mogoa
  • G F Stegmann
  • A J Guthrie
چکیده

The effects of acute exposure to 3 different temperature and humidity conditions on arterial blood-gas and acid-base balance in goats were investigated after intravenous bolus administration of xylazine at a dose of 0.1 mg/kg. Significant (P<0.05) changes in the variables occurred under all 3 environmental conditions. Decreases in pH, partial pressure of oxygen and oxyhaemoglobin saturation were observed, and the minimum values for oxygen tension and oxyhaemoglobin saturation were observed within 5 min of xylazine administration. The pH decreased to its minimum values between 5 and 15 min. Thereafter, the variables started to return towards baseline, but did not reach baseline values at the end of the 60 min observation period. Increases in the partial pressure of carbon dioxide, total carbon dioxide content, bicarbonate ion concentration, and the actual base excess were observed. The maximum increase in the carbon dioxide tension occurred within 5 min of xylazine administration. The increase in the actual base excess only became significant after 30 min in all 3 environments, and maximal increases were observed at 60 min. There were no significant differences between the variables in the 3 different environments. It was concluded that intravenous xylazine administration in goats resulted in significant changes in arterial blood-gas and acid-base balance that were associated with hypoxaemia and respiratory acidosis, followed by metabolic alkalosis that continued for the duration of the observation period. Acute exposure to different environmental temperature and humidity conditions after xylazine administration did not influence the changes in arterial blood-gas and acid-base balance.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Clinical, cardiopulmonary and haemocytological effects of xylazine in goats after acute exposure to different environmental temperature and humidity conditions.

This study was carried out to assess the influence of xylazine administration on clinical, cardiopulmonary and haemocytological variables after acute exposure to different environmental conditions. Xylazine hydrochloride was administered intravenously at 0.1 mg/kg body mass to 6 clinically healthy, castrated male goats. All animals were exposed for 60 min to 3 sets of climatic conditions: 14 de...

متن کامل

TEMPERATURE CORRECTION OF ARTERIAL BLOOD pH AND CO2 TENSION IN NEWBORN INFANTS: A NEW SOLUTION FOR AN OLD PROBLEM

The acid-base status and arterial blood gas change with temperature variation. To determine the changes in arterial pH and pC02, arterial blood samples of 50 neonates with different clinical conditions were examined at temperatures of 35 to 42°C with an increment of 0.5° C, which resulted in two nonlinear equations with perfect fit on data. The temperature correction factors of these equati...

متن کامل

ارزیابی وضعیت گازهای خون شریانی در شرایط هیپوباریک و مقایسه آن با شرایط نرمال در خلبانان جنگنده شکاری

Background and purpose : Arterial blood gases ( Arterial blood gas [ABG] ) One of the most important Laboratory tests to determine the status PH the amount of oxygen and carbon dioxide blood levels of bicarbonate. Also, hemoglobin and serum lactate and electrolytes and also won the Test . Height and air pressure can vary on ABG and its surface, low pressure conditions at high altitude pilots pl...

متن کامل

The study of humidity effect on carbon dioxide gas sensing properties of zinc oxide nanowires assisted by polyvinyl alcohol network at room temperature

In this research, Zinc oxide (ZnO) nanostructures were synthesized by low cost hydrothermal method. The grown ZnO nanostructures had a dispersed distribution with nanowire morphology and the specific surface area of about 7 m2.gr-1 which they have crystalized in hexagonal wurtzite structure. ZnO nanowires/polyvinyl alcohol network (ZP) on the epoxy glass substrate with cu-interdigited electrods...

متن کامل

Models for estimating phytoplankton population densities under different environmental conditions with emphasis on climatic factors

The aim of this study is to determine the effect of environmental conditions with emphasis on the main meteorological factors (air temperature variables, sunshine hour, and humidity), on phytoplankton communities. As important primary producers in aquatic ecosystems, phytoplankton communities could be affected by several factors. Environmental factors play the major role in occurrence and diver...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Journal of the South African Veterinary Association

دوره 71 4  شماره 

صفحات  -

تاریخ انتشار 2000